The Swans are six games without a win and head to Villa Park to take on a side who are rooted in the bottom three of the division and in desperate need of a win to lift their spirits.
And the Swans joint leading scorer will be looking to get one over on his brother and end that run of form for the Swans as they look to secure their first win since beating Manchester United at the end of August.
“At the end of the day we are family, but when we get onto the pitch it’s about business and fighting for your team-mates and fans,” said big brother Ayew.
“We have played against each other before and it has been a bit weird.
“I lost when we played against each other in France last season when he was at Lorient – he scored two and I got one – so I hope it isn’t like that on Saturday.
“He can have a good game, as long as we win.”